The main aim of our research is to discover the core theoretical and juridical aspects of Euroregional co-operation on the eastern border of the European Union. The main objectives of our research are to discover the essence of the institutional system of the Carpathian Euroregion and the problems around Euroregional co-operation as related to Ukraine. By using the methodology of functional analysis and analogy, and a comparative analysis of the systematic research of Euroregional co-operation we will examine on the essence and experience of Euroregional co-operation.Decentralization is a structurally decisive factor as related to Euroregional cooperation development in Ukraine and efficiently acting Euroregions of Ukraine in the European comparative context. It means that Euroregions are built from below, based on imitative from self-government authorities; maximum involvement of co-operation of regions; delegating real competencies to self-government authorities of Ukraine.This article is focused on analyzing Euroregional co-operation. As of today Euroregional co-operation in Ukraine is a tool for the development of border regions while at the same time a factor for implementing its European integration aspirations.